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Circulating apoptotic endothelial cell-derived microparticles are predicted metabolically unhealthy obesity
Conclusion: in the investigation we found that the increased number of CD31+/Annexin V+ and CD144+/ Annexin V+ EMPs added to the based predictive model (HOMA-IR) may predict transformation of Met-HO into Met-UHO.
Good manufacturing practice-compliant isolation and culture of human bone marrow mesenchymal stem cells
The results showed that 100% samples of bone marrow can be successfully cultured to produce BM-MSCs. Obtained cells exhibited the MSC phenotypes, and maintained the stable and normal karyotype up to 10th passages, and failed to cause tumor in the mouse models. This research provided an advanced protocol for clinical applications of BM-MSCs.